Regulations, standards, and guidance for nanomaterials have been issued by various groups, including international standards organizations, government agencies, and research centers. This page is intended to present a survey of publications and available information from these diverse entities. The Nanomaterial Registry attempts to stay apprised of major publications in the three areas of regulations, standards, and guidance. However, as the list of standards and guidance is ever evolving, please contact us if you know of relevant information that should be featured on this site by sending us feedback via the Contact Us page.


National Institute of Standards and Technology (NIST)
Several nanomaterials investigated by NIST have been curated into the Nanomaterial Registry. Below are the NIST titles and their corresponding Nanomaterial Registry record IDs.

NIST title Nanomaterial Registry record NIST description
Standard Reference Materials
1964 NR971 Polystyrene Spheres, Nominal 60 nm Diameter
1963a NR970 Polystyrene Spheres, Nominal 100 nm Diameter
1898 NR968 Titanium Dioxide Nanomaterial
Reference Materials
8013 NR965 Gold Nanoparticles, Nominal 60 nm Diameter
8012 NR964 Gold Nanoparticles, Nominal 30 nm Diameter
8011 NR963 Gold Nanoparticles, Nominal 10 nm Diameter

International Organization for Standardization (ISO)
The Technical Committee on Nanotechnologies (TC 229) has published and is publishing many standards for nanomaterial vocabulary and characterization.

American Society for Testing and Materials (ASTM)
ASTM has a committee dedicated to nanotechnology, Committee E56, which has produced two documents for the community's use:

  • Standard Terminology Relating to Nanotechnology, and
  • Standard Guide for Handling Unbound Engineered Nanoscale Particles in Occupational Settings.

In addition, Committee E56 has produced several standards for the analysis of nanomaterial characteristics, evaluating their effect in certain biological systems, and the occupational handling of nanomaterials.

International Electrochemical Commission (IEC)
The IEC Technical Committee on Nanotechnology Standardization for electrical and electronic products and systems (TC113) works in conjunction with its sister committee, TC 229, in ISO and has published many standards on the vocabulary and characterization of nanomaterials in relation to electrical and photonic applications.


National Nanotechnology Initiative (NNI)
The NNI consists of the efforts of 25 U.S. government agencies in nanotechnology research and regulatory activities.

The GoodNanoGuide was created to help manufacturers using nanomaterials to operate with good practices to safely handle them. This resource is maintained by Oregon State University and the National Institute for Occupational Safety and Health (NIOSH).

Organisation for Economic Cooperation and Development (OECD)
The Series on the Safety of Manufactured Nanomaterials has many publications available to the public, including the Guidance Manual for the Testing of Manufactured Nanomaterials: OECD's Sponsorship Programme.

U.S. Food and Drug Administration (FDA)
The FDA's website on nanotechnology includes a document on guidance for nanotechnology in FDA-regulated products.

U.S. Occupational Safety and Health Administration (OSHA)
While OSHA does not currently have nanotechnology-specific regulations, there are several suggestions and resources listed here for the current research initiatives.

European Commission
The Joint Research Centre has published several documents on the regulatory and human health research of nanomaterials.

National Institute of Advanced Industrial Science and Technology (AIST)
The Research Institute of Science for Safety and Sustainability at Japan's AIST has published several documents on risk assessment and protocols for manufactured nanomaterials.

Other Organizations
The U.S. White House has produced several documents regarding nanotechnology via the Office of Science and Technology Policy.

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