Nanomaterial Similarity The Nanomaterial Registry provides a method for matching nanomaterial entries by their degree of similarity. By clicking the “Find Similar Nanomaterials” button on any individual record’s page, you will receive a list of nanomaterials that are at least 10% similar to the first nanomaterial.

The rules currently used for identifying the similarity between any two nanomaterials are:

  1. If Shape is defined for both nanomaterials, it must be equal, regardless of all other data.
  2. If the nanomaterials have the same Instance of Characterization for Size and the Instance of Characterization is not “As Processed,” the nanomaterials are a 30% match.
    • If there is no Size information, look for Aggregation/Agglomeration State.
    • If the nanomaterials have the Instance of Characterization “As Processed” for Size, and the Techniques for characterization are the same (e.g. DLS), the nanomaterials are only 22.5% similar.
  3. If the Size values are within 10%, those two nanomaterials are an additional 15% match.
    • But if the Size values are within 25%, those two nanomaterials are only an additional 10% match.
  4. If both nanomaterials have the same Material Type for their most outward chemistry, they are an additional 25% similar.
  5. If Isoelectric Point value is within 10% and the nanomaterials were characterized in the same way, another 15% similarity can be added.
    • But if Isoelectric Point value is only within 25% and the nanomaterials were characterized in the same way, only another 10% similarity can be added.

NOTE: The maximum % similarity possible at this time is 85%.

As the Registry grows, we will be working on expanding the rules in key areas of data, most importantly the Instance of Characterization and its fields of metadata (e.g., Manufacturer, Product Name, and Lot #). There is a lot of potential in this area of data and we hope to have much improved matching throughout as the quality of the data improves.

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